Moderna Wings It: Bird Flu Vaccine in the Works!
In a bid to outflank bird flu, the U.S. government has awarded Moderna $176 million to develop a new mRNA vaccine, banking on the same tech that helped tackle COVID-19.
With over 130 herds afflicted in a dozen states and a handful of dairy workers falling ill, the U.S. government is leveraging its rapid response funds to tap into the magic of mRNA once again. Though we won’t see this bird flu vaccine until next year at the earliest, health officials stress its potential to adapt quickly to other viral misadventures. And just in case you were worried—the milk supply is still clucking along, safe and sound.
The unprecedented bird flu outbreak has sent medical and governmental authorities into a flurry of activity. Affecting over 130 herds across 12 states, the virus has managed to grip both livestock and human populations, although the latter on a very small scale. Remarkably, there have been only three human cases reported in 2024, all involving dairy workers; this brings the total number of human cases in the U.S. to four. Officials reassure the general population that the risk remains low and the commercial milk supply is safe. Not that anyone needed another reason to avoid close contact with sick cows, but it’s certainly a relief!
Health officials were keen to reassure a jittery public that the risk to the general population remains low. The commercial milk supply is particularly under scrutiny, but officials have declared it safe—there's no need to switch to almond milk unless it's just your preference.
In response to the outbreak, the Department of Health and Human Services (HHS) announced funding for Moderna through the Federal Rapid Response Partnership Vehicle. This $176 million windfall is set to help the pharmaceutical company flex its mRNA muscles. According to HHS, mRNA technology was instrumental during the COVID-19 response, and they are optimistic it can be repurposed to tackle this avian menace.
However, it is important to temper expectations; the vaccine is currently in its early stages of development and will not be ready until at least next year. Preliminary results on vaccine safety and immunogenicity from their initial studies are expected in 2024. Caitlin Rivers, a notable expert, stressed the importance of diversifying the types of bird flu vaccines but lightly quipped that the government’s efforts are moving at a snail's pace.
Interestingly, the government's existing stockpile of 4.8 million doses of bird flu vaccines employs traditional vaccine technology. This highlights the potential for a significant shift, should Moderna's mRNA approach prove successful. The ability of mRNA vaccines to be adapted quickly makes them a versatile tool in addressing new and emerging infectious diseases. It's like giving our medical toolbox a tech upgrade from a flip phone to a smartphone.
More than 780 individuals exposed to the infected cows have been monitored as part of the efforts to contain and study the outbreak. Among these, 53 people were specifically tested for the H5N1 virus. Continuous monitoring and testing are ongoing to ensure that any potential spread is swiftly managed—though the cows seem to be enjoying all the extra attention.
Health officials remain vigilant, leveraging lessons from past epidemics to better prepare for future viral threats. Whether you find yourself in a grocery store or at a farmers' market, rest assured that experts are on the frontline, fighting to develop tools and strategies to safeguard public health. If you find yourself doom-scrolling, perhaps stop and appreciate that while the wheels of science may sometimes turn slowly, they often lead us out of dire straits.
As we await the roll-out of Moderna's mRNA wizardry, it’s worth noting the broader implications. Should the mRNA bird flu vaccine prove effective, it could herald a new era in how we prepare for and combat animal-borne diseases. While it may appear we’re perpetually one news headline away from another crisis, the rapid adaptability of mRNA technology offers a glimmer of hope in our ongoing battle against not just bird flu, but future pandemics as well.